@article{DMR5381,
author = {Xiaoyi Fang and Guangming Li and Airun Zhang and Hanni Lin and Min Wang and Yongheng Chen and Yuguang Li},
title = {Leptin in breast milk prevents hyperlipidemia in adult female rats born small for gestational age},
journal = {Digestive Medicine Research},
volume = {2},
number = {0},
year = {2019},
keywords = {},
abstract = {Background: To investigate the effect of breast milk leptin on prevention of hyperlipidemia in adult rats born small for gestational age (SGA).
Methods: SGA rat pups were cultivated through restricted feeding of dams and were randomly divided into four groups, named SB, SF, SFL, and SBLA, which were fed with breast milk, formula milk, leptin-added-formula milk, and breast milk with a leptin antagonist, respectively, within 20 days after birth. Appropriate-for-gestational-age (AGA) pups were fed with breast milk and designated as the AB group. Body biometrics and serum leptin, total cholesterol (TC), and triglyceride (TG) levels were quantified on days 18, 30, 90, and 120 of life.
Results: Compared with the breast-fed AGA rats, the breast-fed SGA rats had lower weight and body mass index (BMI) at all age groups and higher TC on days 30 and 90 (P},
issn = {2617-1627}, url = {https://dmr.amegroups.org/article/view/5381}
}